improving solubility
Novartis' Jennifer Sheng on Solubility Modelling & the Future of Solubilisation
December 10 by Andrea CharlesPoor solubility is an obvious barrier to advancing potentially efficacious drug candidates. In this interview Jennifer Sheng, Fellow at Novartis, discusses the most efficient approaches for...
Survey: Improving Solubility 2012
April 27 by Pharma IQ SurveysIn preparation for the 8th Annual Improving Solubility Summit, taking place in June, Pharma IQ would like to invite you to take part in a short survey. The survey consists of no more than 8 questions...
Identifying Formulations to Progress Compounds Solubility
March 20 by Niamh MadiganSolving solubility problems is one of the leading challenges in drug development, as poorly soluble compounds are estimated to account for 60% of compounds. Preclinical development encompasses the a...
How to Predict the Absorption Rate of New Chemical Entities
February 23 by Pharmaceuticals & Biotechnology EditorCurrent estimates indicate that 40% of drugs on the market place and 90% of APIs in development are poorly soluble. David Elder, Externalisation Director for GlaxoSmithKline and Pharma IQ Advisory B...
Oral Lipid Formulations - Enhancing the Bioavailability of Poorly Water Soluble Drugs
February 03 by Amber ScorahLipid formulations have gained momentum in recent years as an efficient means for improving solubility of new chemical entities, but ensuring the stability of these systems can prove challenging. Dr...
Drug Discovery and the Market Today Part 3: The Focus on Solubility
June 09 by Pharmaceuticals & Biotechnology EditorDrug Discovery and the Market Today Part 1: An Overview of Externalisation in the Pharma Industry
June 08 by Pharmaceuticals & Biotechnology EditorNanotechnology Puts Drug Solubility Under the Microscope
June 04 by Pharma IQOne aspect of solubility which continues to get much attention is nanotechnology. The concept sees pharmaceutical firms work on a molecular scale in an effort to engineer the best possible formula...
Harnessing the Potential of Nanotechnology to Aid in the Delivery of Poorly Soluble Compounds
April 25 by Ameet AmbarkhaneAmeet Ambarkhane, Principal Scientist at Novartis, joins Pharma IQ to discuss harnessing the potential of nanotechnology to aid in the delivery of poorly soluble compounds and bottlenecks in early d...
Optimizing Solubilization of Lipid Formulations in the GI Tract
April 25 by René HolmWith the advent of improved techniques for drug discovery, there has been a transition towards new chemical entities to be hydrophobic and non-polar, which in turn has made solubilization of these e...