The Trials and Tribulations of Comparator Sourcing for Clinical Trial Materials

The numbers of clinical trials that compare two active drugs, rather than testing a new drug against a placebo, are increasing. Comparator trials are chosen for two main reasons. Firstly, there may be ethical reasons why using a placebo in place of a genuine treatment is not preferred. For example, if subjects have existing conditions that could worsen if their treatment is stopped for any period of time. Secondly, there is a general increase in focus on the comparative effectiveness of... To continue reading this story Click Here