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Bioavailability

Bioavailability is used to describe the fraction of an administered dose of unchanged drug that reaches the systemic circulation, one of the principal pharmacokinetic properties of drugs. By definition, when a medication is administered intravenously, its bioavailability is 100%.[1] However, when a medication is administered via other routes (such as orally), its bioavailability decreases (due to incomplete absorption and first-pass metabolism) or may vary from patient to patient (due to inter-individual variation). Bioavailability is one of the essential tools in Pharmacokinetics, as bioavailability must be considered when calculating dosages for non-intravenous routes of administration.

Anders Fuglsang

Ahead of the 2nd Annual Bioequivalence and Bioavailability Studies conference, Pharma IQ caught up with Anders Fuglsang from FuglsangPharma. Fuglsang is a former EU regulator (clinical assessor) and managed the international group of assessors...

Contributor: Anders Fuglsang
07/14/2011 08:00:00 PM EDT
Pharma IQ

If the trends that have been seen in the pharmaceutical industry over the past few years prove anything, it is that drug development companies are increasingly recognising the value of teamwork. There is plenty of evidence that businesses in the...

Contributor: Pharma IQ
09/02/2010 08:00:00 PM EDT