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Biomarker

A Biomarker is defined as anything that can be used as an indicator of a particular disease state or some other biological state of an organism. A biomarker can be a substance that is introduced into an organism as a means to examine organ function or other aspects of health. For example, rubidium chloride is used as a radioactive isotope to evaluate perfusion of heart muscle. It can also be a substance whose detection indicates a particular disease state, for example, the presence of an antibody may indicate an infection. Biomarkers can be specific cells, molecules, or genes, gene products, enzymes, or hormones.

The Road To ‘Personalised Medicine’ with AstraZeneca's Duncan McHale

Duncan McHale, Vice-President for Personalised Healthcare and Biomarkers, Astrazeneca, joins Helen Winsor of Pharma IQ. In this interview he discusses the importance of biomarker discovery & validation, how close we are to ‘Personalised...

08/16/2011 08:00:00 PM EDT
Helen Winsor

Reto Ossola, Group Leader for Biomarker Research at Biognosys, joins Pharma IQ to discuss the main challenges in biomarker development and some key ways to address these. Ossola offers some best practice tips for assessing and working with a CRO...

Contributor: Helen Winsor
09/07/2010 08:00:00 PM EDT
Pharma IQ

Reto Ossola, Group Leader for Biomarket Research at Biognosys, joins Helen Winsor from Pharma IQ, to discuss phase I clinical development. He outlines where he sees the main challenges in biomarker development at the moment and discusses some key...

Contributor: Pharma IQ
09/05/2010 08:00:00 PM EDT