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Efficacy

Efficacy, or intrinsic activity (IA), is defined as the relative ability of a drug-receptor complex to produce a maximum functional response. This use of the word "efficacy" was introduced by Stephenson (1956) to describe the way in which agonists vary in the response they produce, even when they occupy the same number of receptors. High efficacy agonists can produce the maximal response of the receptor system while occupying a relatively low proportion of the receptors in that system.

Marc Descamps

Marc Descamps, Professor in Solid State Physics at Université Lille and Lead of the European ID Network for Improved Drug Efficacy and Availability, joins Pharma IQ to discuss the use of amorphous pharmaceutical materials to improve necessary...

Contributor: Marc Descamps
08/18/2011 08:00:00 PM EDT
Helen Winsor

Marc Descamps, Professor in Solid State Physics at Université Lille and Lead of the European ID Network for Improved Drug Efficacy and Availability, joins Helen Winsor from Pharma IQ, to discuss the use of amorphous pharmaceutical materials to...

Contributor: Helen Winsor
05/31/2011 08:00:00 PM EDT
Pharma IQ

Clinical trials may be one of the most fundamental parts of drug development work carried out in the pharmaceutical industry, but they still remain a complicated area for pharma companies to address. The design of trials plays an important role...

Contributor: Pharma IQ
09/28/2010 08:00:00 PM EDT