Pharma IQ Glossary: Microbial Barrier

A Microbial Barrier, or Microbiological Barrier, prevents the migration of microbial contaminants. The tests used with microbiological barrier systems include air sampling, surface sampling, filter and air incinerator testing, and gas-tightness testing. Microbiological barrier systems can be classified according to purpose, size, and degree of containment. Sterilization and decontamination agents are used with barrier systems for initial or terminal treatment, for the treatment of supplies and equipment moved in or out of the system, and for the maintenance of its microbiological state during use.