Solving Problems Posed by Large Molecules

Pharma IQ: In predictive toxicology what difference does the small molecule versus large molecule make? Stephen Kirk: The biggest difference is with regards to the small molecule there’s more of a structured process for predictive pre-clinical toxicological studies and you’re looking more for kind of off target toxicity, whereas with a larger molecule it’s very specific, so you’re looking more for an exaggerated pharmacology type response and looking for specific t...
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