Clinically Relevant Drug Transporters: Understanding DDI with a View to Better Prediction and Control
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Clinically Relevant Drug Transporters: Understanding DDI with a View to Better Prediction and Control
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How is the industry seeking to understanding DDI with a view to better prediction and control? How has the current technology landscape changed following the publication of the ITC white paper? What progress do you expect we will see in clinically relevant drug transporters in 2012? Drug transporters exert a vital influence on drug absorption, disposition, metabolism and elimination and are seen as an essential part of predicting drug disposition. However, identifying and employing the right membrane transporters remains a challenge as does the interpretation and translation of transport data. In this interview Dr. James Clarke, Senior Scientist, GlaxoSmithKline, speaks to Andrea Charles from Pharma IQ, about the biggest challenges for clinically relevant drug transporters.
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