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Mads Ropke, Senior Scientist at LEO Pharma, joins Helen Winsor from Pharma IQ to discuss companion diagnostics and how we can ensure the delivery of safer and more efficacious drugs to market. First, he outlines how companion diagnostics can help us to administer the right drug at the right time in the right dose to the right patient? In this developing area, companion diagnostics can sometimes prove costly and difficult to implement and utilise effectively, so Ropke runs through some of the main problems and challenges. He advises on the vital stages in translating biomarkers from the laboratory to the clinic – and the best ways of successfully validating them. Ropke reports on some of the innovative ways to use companion diagnostics to advance drug development and improve efficacy. Finally, he offers a few tips on finding, managing and extracting the most value out of diagnostics partnerships.