Identifying Formulations to Progress Compounds Solubility

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Niamh Madigan

Solving solubility problems is one of the leading challenges in drug development, as poorly soluble compounds are estimated to account for 60% of compounds. Preclinical development encompasses the activities that link the drug discovery process in the lab to initiation of human clinical trials. Anuj Kuldipkumar, PhD, Scientist II at  Vertex Pharmaceuticals, identifies steps to take in developing toxicology and safety studies to identify potential target organs for
adverse effects.


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