Trends in Computational Toxicology & Critical Success Factors for Transporter Studies
In this exclusive interview Tobias Noeske, Associate Principal Scientist from AstraZeneca, speaks to Andrea Charles from Pharma IQ. Noeske describes how AstraZeneca are reducing compound attrition rates arising from drug-induced liver injury (DILI). DILI is a major cause for attrition in clinical trials, which can cost hundreds of million of dollars in the late stages of drug development.
Noeske explains how in silico models can identify and mitigate compound-related safet...
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