Using Next-Generation DNA Sequencing Methods

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Using Next-Generation DNA Sequencing Methods

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Although more than a thousand bacterial genomes have been sequenced, our understanding of bacterial transcriptomes has lagged far behind. Transcript structure, operon linkages, and absolute mRNA abundance information all provide valuable insights into gene function and regulation, but these aspects of the prokaryotic transcriptome have only been explored on a large scale in a few instances. In this Pharma IQ interview, Dr. Nicholas H. Bergman, Principal Investigator and Genomics Team L...

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