What Are the Advantages and Disadvantages of Human Embryonic Kidney (HEK) Cells for the Analysis of Uptake Transporters?
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Dr. Jörg König from the Institute for Experimental and Clinical Pharmacology and Clinical Toxicology at Friedrich-Alexander-University Erlangen-Nürnberg, Germany, speaks to Rebecca Maschke from Pharma IQ, about the analysis of transporter-mediated drug-drug interactions, different kinds of transporter-mediated drug-drug interactions, and the transferability of in vitro generated transport and inhibition data to the in vivo situation (IVIVE).
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