What Are the Advantages and Disadvantages of Human Embryonic Kidney (HEK) Cells for the Analysis of Uptake Transporters?




Dr. Jörg König from the Institute for Experimental and Clinical Pharmacology and Clinical Toxicology at Friedrich-Alexander-University Erlangen-Nürnberg, Germany, speaks to Rebecca Maschke from Pharma IQ, about the analysis of transporter-mediated drug-drug interactions, different kinds of transporter-mediated drug-drug interactions, and the transferability of in vitro generated transport and inhibition data to the in vivo situation (IVIVE).
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